BASES FARMACOLÓGICAS DE LAS INTERACCIONES MEDICAMENTOSAS
Arlette Linares Borges, Higinio Alemán Aguilar, Jesús M. RodrÃguez Muñiz, Luis M. MartÃn GarcÃa, Pedro M. Milián Vázquez
Resumen
Se revisó el tema de interacciones medicamentosas para compilar información necesaria para la práctica médica. Se describen varias clasificaciones de interacciones, y se enfatiza en la clasificación según mecanismos de producción; se explican y ejemplifican las interacciones farmacéuticas por incompatibilidad quÃmico-fÃsica, las interacciones farmacocinéticas por cambios en la absorción, distribución, metabolismo y excreción; se incluyen los factores que pueden modificar cada uno de estos procesos y las interacciones farmacodinámicas a nivel del receptor (antagonismo fisiológico, antagonismo farmacológico competitivo y no competitivo, agonismo parcial, desensibilización e hipersensibilización) o por sinergismos funcionales.
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Creative Commons Reconocimiento-NoComercial 4.0 Internacional .
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