COLITIS ULCERATIVA Y PIODERMA GANGRENOSO
Dra. Milagros del Carmen Hernández Urra, Dr. Mario Hernández Cubas, Dra. Ketty Yanet Monteagudo Hernández
Resumen
La colitis ulcerosa (CU) es una enfermedad caracterizada por una inflamación difusa y crónica de la mucosa del colon que afecta al recto en el 95 % de los pacientes, y se extiende en sentido proximal y continuo1. ClÃnicamente se caracteriza por diarrea con sangre, moco o ambos, en las heces, y evoluciona en forma de brotes de actividad2.
Existen una serie de manifestaciones extraintestinales asociadas que es importante reconocer, ya que en ocasiones aparecen antes de que se inicien las manifestaciones clÃnicas intestinales; estas pueden ser articulares, dérmicas, oftalmológicas, hepatobiliares y renales
2,3 Entre las dermatológicas, la complicación más grave es el pioderma gangrenoso, con una frecuencia de 2 a 12 %, que tiene un curso independiente de la enfermedad intestinal y, por lo común, se asocia a enfermedad grave. Su localización más frecuente es en los miembros inferiores, y puede ser única o múltiple
4,5. Su control terapéutico es complejo, y precisa a menudo de inmunosupresores
6,7.
Este artÃculo está licenciado bajo la licencia
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